CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis.
Where this comes from
- Record sourced from PubMed, PMID 38109675.
- Also identified by DOI 10.1093/bioinformatics/btad759 and PMC identifier 10749757.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
High-throughput sequencing technologies have enabled cross-species comparative transcriptomic studies; however, there are numerous challenges for these studies due to biological and technical factors. We developed CoSIA (Cross-Species Investigation and Analysis), a Bioconductor R package and Shiny app that provides an alternative framework for cross-species transcriptomic comparison of non-diseased wild-type RNA sequencing gene expression data from Bgee across tissues and species (human, mouse, rat, zebrafish, fly, and nematode) through visualization of variability, diversity, and specificity metrics. https://github.com/lasseignelab/CoSIA.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- Software
- Computational Biology