Seroreversion to Chlamydia trachomatis Pgp3 Antigen Among Children in a Hyperendemic Region of Amhara, Ethiopia.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 38134305.
- Also identified by DOI 10.1093/infdis/jiad602 and PMC identifier 11326833.
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Abstract
Monitoring trachoma transmission with antibody data requires characterization of decay in IgG to Chlamydia trachomatis antigens. In a 3-year longitudinal cohort in a high-transmission setting, we estimated a median IgG half-life of 3 years and a seroreversion rate of 2.5 per 100 person-years (95% confidence interval, 1.6-3.5). Clinical Trials Registration NCT02754583.
Medical subject headings
- Antibodies, Bacterial
- Antigens, Bacterial
- Bacterial Proteins
- Chlamydia trachomatis
- Immunoglobulin G
- Trachoma