Unusual Presentation of Solitary Penile Metastasis of Prostate Cancer on 68 Ga-PSMA PET/CT.

Bin Essa, Noora Essa; Alderaibi, Alaa Khalid; Fraioli, Francesco · Clin Nucl Med · 2024

case_report · Level V

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Abstract

A 75-year-old patient was referred with biochemical recurrence for prostate cancer. The patient underwent 68 Ga-PSMA (prostate-specific membrane antigen) PET/CT scan, which revealed a focal PSMA activity in the proximal left lateral penile margin. Although a subsequent ultrasound did not identify the abnormality, MRI pelvis revealed a 10-mm lesion in the left proximal corpus cavernosum. This lesion was consistent with metastatic acinar adenocarcinoma of the prostate on postresection histopathology. This unusual presentation of asymptomatic, histopathology-proven, penile solitary metastases was documented 3 years after robotic-assisted laparoscopic prostatectomy and pelvic external beam radiotherapy.

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