Improving cellular diversity in human cerebellar organoids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38181748.
- Also identified by DOI 10.1016/j.stem.2023.12.007.
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Abstract
The developing human cerebellum has a greater diversity of progenitor types than that of the mouse, necessitating a human-based model for studying cerebellar development and disease. Atamian et al.<sup>1</sup> developed a 3D organoid model of cerebellar development, which recapitulates many cell types found in the developing human cerebellum, including Purkinje-neuron-like cells.
Medical subject headings
- Organoids
- Cerebellum