YB-1: the Jekyll and Hyde of kidney disease?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38182288.
- Also identified by DOI 10.1016/j.kint.2023.10.020.
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Abstract
Y-box-binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box-binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.
Medical subject headings
- Y-Box-Binding Protein 1
- Kidney Diseases