Unanswered questions following reports of secondary malignancies after CAR-T cell therapy.

Levine, Bruce L; Pasquini, Marcelo C; Connolly, John E; Porter, David L; Gustafson, Michael P; Boelens, Jaap J; Horwitz, Edwin M; Grupp, Stephan A et al. · Nat Med · 2024

editorial · Level V

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Abstract

Reports of T cell malignancies after CAR-T cell therapy should be investigated, but existing data from follow-up studies suggest a low risk compared with other cancer treatments.

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