A holistic view of the malignant organism we call glioblastoma.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 38242083.
- Also identified by DOI 10.1016/j.cell.2023.12.021.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Tumors are not simply a chaotic mass of mutated cells but can follow complex organizational principles, including in space. In this issue of Cell, Mathur and colleagues reconstruct a 3D genomic, epigenomic, and transcriptomic spatial cartograph of glioblastoma, offering a "whole-tumor" perspective with patterns of clonal expansion that are embedded in neurodevelopmental hierarchy.
Medical subject headings
- Glioblastoma
- Brain Neoplasms