FDG-Avid Periprosthetic Particle Disease Mimicking Osteosarcoma Recurrence.

Dong, Ziqian; Guo, Ziyu; Guan, Meichao; Zhang, Yingjie; Xie, Peng · Clin Nucl Med · 2024

case_report · Level V

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Abstract

A 24-year-old man with a history of osteosarcoma presented with swelling in his right thigh for more than 1 year. 18 F-FDG PET/CT demonstrated increased FDG uptake in multiple juxtacortical masses around the prosthesis, which highly suggested the possibility of osteosarcoma recurrence. A biopsy was performed, and the pathology confirmed the diagnosis of particle disease. The current case indicates that particle disease should be considered when interpreting the PET/CT images with high FDG uptake around the prosthesis.

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