Amount of Gleason Pattern 3 Is Not Predictive of Risk in Grade Group 2-4 Prostate Cancer.

Vickers, Andrew J; Assel, Melissa; Cooperberg, Matthew R; Fine, Samson W; Eggener, Scott · Eur Urol · 2024

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Abstract

We investigated whether total Gleason pattern 3 or the proportion of Gleason pattern 4 on biopsy is a significant predictor of adverse pathology. Our findings suggest that quantifying the amount rather than the proportion of Gleason pattern 4 would improve grade group assignment for decision-making in localized prostate cancer.

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