MALT Lymphoma in Histologic Transformation: FDG-Avid but Pentixafor-Negative.
case_report · Level V
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- Record sourced from PubMed, PMID 38306380.
- Also identified by DOI 10.1097/RLU.0000000000005057.
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Abstract
An 81-year-old woman experienced compression symptoms due to diffuse enlargement of the thyroid gland. The cytopathological results of thyroid fine-needle suggested malignancy. Therefore, she underwent bilateral thyroidectomy. Postoperative pathology indicated mucosa-associated lymphoid tissue (MALT) lymphoma. Three months later, she found a progressively enlarged mass in her neck. The biopsy showed MALT lymphoma with highly aggressive B-cell lymphoma transformation. 18F-FDG PET/CT showed increased metabolism in multiple lymph nodes. However, some of these lymph nodes were negative in 68Ga-pentxafor PET/CT. Our case demonstrated that 68Ga-pentixafor may have limited value in evaluating MALT lymphoma transformation.
Medical subject headings
- Lymphoma, B-Cell, Marginal Zone
- Coordination Complexes