Al18F-NOTA-Octreotide PET/CT and 18F-FDG PET/CT for Detecting Cerebellar Hemangioblastoma in a Patient With Von Hippel-Lindau Disease.
case_report · Level V
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- Record sourced from PubMed, PMID 38306383.
- Also identified by DOI 10.1097/RLU.0000000000005042.
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Abstract
Von Hippel-Lindau disease is a hereditary syndrome associated with various benign and malignant tumors, including hemangioblastomas. A 42-year-old man with a history of Von Hippel-Lindau disease underwent surgery for pancreatic neuroendocrine tumor and renal clear cell carcinoma and was recommended to undergo Al18F-NOTA-octreotide and 18F-FDG PETCT examination to assess potential metastases. 18F-FDG PET/CT showed low uptake in the right cerebellum, which demonstrated increased Al18F-NOTA-octreotide activity. Cerebellar mass resection surgery was performed. Pathological result was consistent with hemangioblastoma. This case report indicates the significant role of Al18F-NOTA-octreotide in the diagnosis of hemangioblastoma.
Medical subject headings
- von Hippel-Lindau Disease
- Hemangioblastoma
- Cerebellar Neoplasms
- Kidney Neoplasms
- Fluorine Radioisotopes
- Organometallic Compounds
- Octreotide