Unraveling the brain's response to COVID-19: How SARS-CoV-2 afflicts dopaminergic neurons.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38306990.
- Also identified by DOI 10.1016/j.stem.2024.01.002.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
COVID-19 patients often display dysfunctions of the nervous system, indicating an effect of SARS-CoV-2 on neural cells. Yang et al. now show that human stem-cell-derived dopaminergic neurons are susceptible to SARS-CoV-2, triggering inflammation and senescence. The study further identifies three FDA-approved drugs capable of reversing these cellular phenotypes.
Medical subject headings
- COVID-19