Behind the Scenes of TOPCAT - Bending to Inform.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 38319229.
- Also identified by DOI 10.1056/EVIDctcs2100007.
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Abstract
Behind the Scenes of TOPCAT - Bending to InformWhen investigators in a 2013 RCT received their unblinded results, the data forced them to make a difficult decision - do they stay within conventional guidelines for data analysis or forge a new path? This Clinical Trial Case Study tells the story of how they dealt with the data dilemma for a heart failure treatment that affects millions of people.
Medical subject headings
- Heart Failure