Subgroup Analyses: Subpar or Sublime?

Hughes, Emily; Takvorian, Katherine S; Dodd, Lori E; Koscal, Natalie; Muller, Daniel; Vining, Tim; Hardin, Charles C; Sacks, Chana A · NEJM Evid · 2022

review · Level V

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Abstract

Subgroup Analyses: Subpar or Sublime?This animated video explores some of the potential pitfalls of performing subgroup analyses in randomized controlled trials and explains how to approach potential findings with caution.