Interface - A New Series from <i>NEJM Evidence</i>.

Hardin, C Corey; Normand, Sharon-Lise · NEJM Evid · 2022

editorial · Level V

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Abstract

Interface - A New Series from <i>NEJM Evidence</i> A major motivation for the launch of <i>NEJM Evidence</i> was a belief that understanding the nuances of study design and execution is key to assessing how the results of a study can, or cannot, influence clinical practice. A corollary is that maximizing clinical utility should be the major focus of study design. It is now widely appreciated that these goals are not optimally achieved solely by relying on binary interpretation of P values in traditional randomized controlled trials.<sup>1</sup>.