Threats to Blinding.

Davies, O M; Takvorian, Katherine S; Muller, Daniel; Vining, Tim; Burke, Alison; Sacks, Chana A; Hardin, Charles C · NEJM Evid · 2022

review · Level V

Where this comes from

Abstract

Blinding is a critical strategy used to limit certain types of bias in randomized controlled trials. This animated video explores the rationale and examines potential threats to keeping group allocation concealed - from study participants and investigators.