Immune Modulation in Sepsis, ARDS, and Covid-19 - The Road Traveled and the Road Ahead.

Leligdowicz, Aleksandra; Harhay, Michael O; Calfee, Carolyn S · NEJM Evid · 2022

review · Level V

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Abstract

Immune Modulation in Sepsis, ARDS, and Covid-19Leligdowicz et al. consider the history and future of immunomodulating therapies in sepsis and ARDS, including ARDS due to Covid-19, and remark on the larger challenge of clinical research on therapies for syndromes with profound clinical and biologic heterogeneity.

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