Colistin - That Was Fun, But Now We're Done.

Bell, Taison D; Park, Stacy C · NEJM Evid · 2023

editorial · Level V

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Abstract

Antimicrobial resistance (AMR) is an increasing global threat with estimates that drug-resistant infections contribute to nearly 5 million deaths worldwide every year.<sup>1</sup> In particular, carbapenem-resistant <i>Acinetobacter baumannii</i> (CRAB) is emerging as a challenging pathogen to treat and has been designated by the World Health Organization as a priority pathogen for the development of new antimicrobial agents.<sup>2</sup> Studies evaluating the efficacy of therapeutic strategies are vitally important in the fight against drug-resistant <i>A. baumannii</i> and other drug-resistant infections.

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