SGLT2 Inhibitors Squeak Out a Win in Patients Post-MI.
rct · Level II
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- Record sourced from PubMed, PMID 38320495.
- Also identified by DOI 10.1056/EVIDe2300318.
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Abstract
James et al<sup>1</sup> report the results of the DAPA-MI (DAPAagliflozin in patients without diabetes mellitus with acute Myocardial Infarction) trial, which studied the efficacy and safety of early initiation of dapagliflozin, a sodium glucose cotransporter-2 (SGLT2) inhibitor, in patients with acute myocardial infarction (MI) without type 2 diabetes (T2D) or heart failure (HF). The trial was conducted within the SWEDEHEART (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) and NICOR (National Institute for Cardiovascular Outcomes Research) registries, leveraging where possible routinely collected health data to augment screening, baseline characteristic ascertainment, and clinical follow-up.
Medical subject headings
- Sodium-Glucose Transporter 2 Inhibitors
- Diabetes Mellitus, Type 2
- Myocardial Infarction
- Heart Failure