Fudging the volcano-plot without dredging the data.
Where this comes from
- Record sourced from PubMed, PMID 38360828.
- Also identified by DOI 10.1038/s41467-024-45834-7 and PMC identifier 10869345.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Selecting omic biomarkers using both their effect size and their differential status significance (<i>i.e.</i>, selecting the “volcano-plot outer spray”) has long been equally biologically relevant and statistically troublesome. However, recent proposals are paving the way to resolving this dilemma.