A case of Stevens-Johnson syndrome treated with oral cyclosporine.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 38361872.
- Also identified by DOI 10.4103/jfmpc.jfmpc_1162_23 and PMC identifier 10866270.
- Licence recorded as CC BY-NC-SA.
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Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respiratory infection, or other viral entities such as cocksackie A, roseola, or herpes simplex virus. We recommend initiating cyclosporine modified treatment, especially in children, upon any suspicion of SJS/TEN in a patient in order to halt the disease progression as early as possible.