Opening the K<sub>V</sub>3.1 gates: A therapeutic strategy for progressive myoclonus epilepsy type 7?

Gandini, Maria A; Zamponi, Gerald W · Cell Rep Med · 2024

basic_science · Level V

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Abstract

Progressive myoclonus epilepsy type 7, a debilitating neurological disorder, is caused by a loss-of-function mutation in the K<sub>V</sub>3.1 channel. Exciting work by Feng et al.<sup>1</sup> utilizes a new knockin mouse model to identify a potential therapeutic intervention.

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