Inflammatory and vaso-occlusive ulcers: Part I - Clinical presentation and diagnosis.

Shakshouk, Hadir; Hines, Alexander; Kody, Shannon; Fett, Nicole; Alavi, Afsaneh; Ortega-Loayza, Alex G · J Am Acad Dermatol · 2024

review · Level V

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Abstract

In this CME, we review 2 specific categories of ulcers: inflammatory (where inflammation is the primary pathologic process leading to ulceration) and vaso-occlusive (where occlusion is the primary process). Inflammatory ulcers include pyoderma gangrenosum and vasculitides, whereas livedoid vasculopathy, calciphylaxis, and Martorell ulcers are vaso-occlusive ulcers. Determining the causes of ulcers in these conditions may require laboratory evaluation, biopsy, and imaging.

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