UCP1 and CKB are parallel players in BAT.

Dong, Meng; Cheng, Ziyu; Jin, Wanzhu · Cell Metab · 2024

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Abstract

It is generally believed that the contributions of the UCP1-independent thermogenic pathways are secondary to UCP1-mediated thermogenesis in BAT. Now, Rahbani et al. demonstrate in vivo that adaptive thermogenesis in brown adipose tissue is regulated by UCP1 and CKB in parallel.

Medical subject headings