18 F-FDG PET/CT in Pediatric Immunoglobulin G4-Related Disease.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 38451857.
- Also identified by DOI 10.1097/RLU.0000000000005151.
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Abstract
A 14-year-old boy presented with severe, nonintentional weight loss, fatigue, and cough. Investigations were notable for raised inflammatory markers and significantly elevated serum immunoglobulin G4 (IgG4). 18 F-FDG PET/CT was obtained for assessment of disease involvement and extent, to exclude differential diagnoses and to guide biopsy. The study demonstrated extensive FDG-avid nodal disease and multisystem organ involvement. Excisional biopsy of a right inguinal lymph node demonstrated reactive changes with numerous IgG4-positive plasma cells consistent with IgG4-related disease. He was commenced on immunosuppressive therapy with consequent weight restoration and symptom resolution.
Medical subject headings
- Fluorodeoxyglucose F18
- Immunoglobulin G4-Related Disease
- Positron Emission Tomography Computed Tomography