Development has the answer: Unraveling psychiatric disorders via thalamocortical organoids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38458174.
- Also identified by DOI 10.1016/j.stem.2024.02.008.
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Abstract
Dissecting the role of the thalamus in neuropsychiatric disorders requires new models to analyze complex genetic interactions. In this issue of Cell Stem Cell, Shin et al. use patient-derived thalamocortical organoids to investigate 22q11.2 microdeletion impact on thalamic development, revealing significant transcriptional dysregulation linked to psychiatric disorders.
Medical subject headings
- Cerebral Cortex
- Mental Disorders