Extravasation After [ 177 Lu]Lu-HA-DOTATATE Therapy.

de Vries-Huizing, Daphne M V; Cheung, Zing J; Hendrikx, Jeroen J M A; Donswijk, Maarten L; Versleijen, Michelle W J · Clin Nucl Med · 2024

case_report · Level V

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Abstract

Extravasation of the radiopharmaceutical during peptide receptor radionuclide therapy infusion is an unwanted infrequently reported event. We present the case of a 74-year old woman with a neuroendocrine tumor who was referred for peptide receptor radionuclide therapy. During intravenous infusion of 7.4 GBq [ 177 Lu]Lu-HA-DOTATATE in the upper right arm, extravasation of the radiopharmaceutical occurred through a displaced intravenous catheter. Planar scintigraphy showed pooling of radioactivity in the right upper arm. After 24 hours, the swelling in the arm was decreased; however, erythema was increased. One week later, symptoms had disappeared, and the patient did not experience any complications during follow-up of 11 months.

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