Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 38471509.
- Also identified by DOI 10.1016/j.cmet.2024.02.008 and PMC identifier 11555857.
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Abstract
Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG codon.
Medical subject headings
- Fibronectins
- Codon, Initiator