The role of surgery and deescalation for HPV-related oropharyngeal cancer.

Contrera, Kevin J; Patel, Mihir R; Burtness, Barbara; Mehra, Ranee; Ferris, Robert L · Cancer · 2025

review · Level V

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Abstract

Recently published and ongoing trials are helping to define the role of transoral robotic surgery for oropharyngeal cancer. Evidence to date supports the use of surgery as a valuable tool in the multidisciplinary deescalation of low-risk human papillomavirus-related oropharyngeal squamous cell carcinoma.

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