SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms.
Where this comes from
- Record sourced from PubMed, PMID 38509328.
- Also identified by DOI 10.1038/s41592-024-02229-2 and PMC identifier 11093726.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
SQANTI3 is a tool designed for the quality control, curation and annotation of long-read transcript models obtained with third-generation sequencing technologies. Leveraging its annotation framework, SQANTI3 calculates quality descriptors of transcript models, junctions and transcript ends. With this information, potential artifacts can be identified and replaced with reliable sequences. Furthermore, the integrated functional annotation feature enables subsequent functional iso-transcriptomics analyses.
Medical subject headings
- Transcriptome
- Molecular Sequence Annotation