Two Germline Pathogenic Variants in Cancer Susceptibility Genes and Their Null Implication in Breast Cancer Pathogenesis: The Importance of Tumoral Homologous Recombination Deficiency Testing.

Rezqallah, Alejandra; Torres-Esquius, Sara; Llop-Guevara, Alba; Cruellas, Mara; Martinez, María T; Romey, Marcel; Denkert, Carsten; Serra, Violeta et al. · JCO Precis Oncol · 2024

case_report · Level V

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Abstract

Homologous recombination proficiency in patients with breast cancer despite germline PALB2/RAD51C pathogenic variants.

Medical subject headings