Unveiling the impact of maternal gestational diabetes mellitus on cord blood CD71+ erythroid cell transcriptome.

Yin, Min; Zhang, Yan; Li, Xinyu; Li, Xia · Pediatr Res · 2024

basic_science · Level V

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Abstract

This study reveals the effects of maternal gestational diabetes mellitus (GDM) on the transcriptome of CD71+ erythroid cells (CECs) in cord blood. It highlights the role of CECs in immunosuppressive function and identifies potential mechanisms linking GDM to adverse outcomes in offspring. This understanding might lead to improved strategies for managing and preventing adverse outcomes in infants born to mothers with GDM.

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