18 F-FET PET/CT in Calcifying Pseudoneoplasm of the Neuraxis : First Case.

Aricò, Demetrio; Giacoppo, Giulia; Bambaci, Michelangelo; Marino, Lorenza; Girlando, Andrea; Sortino, Giuseppe; Leone, Giorgia; Fernandes, Bethania et al. · Clin Nucl Med · 2024

case_report · Level V

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Abstract

A 66-year-old man has been treated in a psychiatric department for 4-5 years for a depressive syndrome, which is associated with poor motor initiative, confusional state, and dysosmia. Dynamic 18 F-FET PET/CT showed only faint uptake of radiotracer just above the background on the left frontal calcific lesion. The time-activity curve of the neoplasms showed a descending pattern. After a left fronto-orbitary minicraniotomy surgery, histology examination concluded for a rare calcifying pseudoneoplasm of the neuraxis (CAPNON). To our knowledge, no data are available on the metabolic behavior of CAPNON in 18 F-FET PET/CT. This case highlighted that a faint uptake and descending pattern on dynamic 18 F-FET PET/CT may be helpful in suspected CAPNON before surgery.

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