Complete Resolution of Locally Advanced Prostate Cancer After Molecular Endoradiotherapy With 177 Lu-PSMA.

Beheshti, Mohsen; Vali, Reza; Zarehparvar Moghadam, Soroush; Amini, HamidReza; Hakiminejad, Masoumeh; Divband, GhasemAli · Clin Nucl Med · 2024

case_report · Level V

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Abstract

A 76-year-old man with castration-resistant prostate cancer underwent 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT for restaging. A large PSMA-avid tumor with invasion to adjacent organs was noted causing gross hematuria and symptomatic anemia. Two cycles of 177 Lu-PSMA were administered, and the patient showed significant reduction of hematuria as well as declining in PSA levels. 177 Lu-PSMA therapy can be a good treatment option in patients with locally invasive tumors.

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