Revolutionizing Daptomycin Dosing: A Single 7-11-Hour Sample for Pragmatic Application.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 38552199.
- Also identified by DOI 10.1093/cid/ciae178.
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Abstract
Precision daptomycin dosing faces clinical implementation barriers despite known exposure-safety concerns with the use of twice the regulatory-approved doses. We propose achieving a single 7-11-hour post-dose plasma target concentration of 30 mg/L to 43 mg/L to be a practical starting point to facilitate precision daptomycin dosing.
Medical subject headings
- Daptomycin
- Anti-Bacterial Agents