Partial reprogramming of the mammalian brain.

Asmussen, Niels C; Schafer, Marissa J · Nat Aging · 2024

basic_science · Level V

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Abstract

Xu and colleagues used partial OSKM reprogramming in aged mice to drive cell-type proportions of the subventricular zone to more youthful levels, which equates to qualified rejuvenation of a neurogenic niche that is defined, in part, by restoration of neuroblast levels.

Medical subject headings