Craniofacial disorders and dysplasias: Molecular, clinical, and management perspectives.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38566929.
- Also identified by DOI 10.1016/j.bonr.2024.101747 and PMC identifier 10985038.
- Licence recorded as CC BY-NC-ND.
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Abstract
There is a wide spectrum of craniofacial bone disorders and dysplasias because embryological development of the craniofacial region is complex. Classification of craniofacial bone disorders and dysplasias is also complex because they exhibit complex clinical, pathological, and molecular heterogeneity. Most craniofacial disorders and dysplasias are rare but they present an array of phenotypes that functionally impact the orofacial complex. Management of craniofacial disorders is a multidisciplinary approach that involves the collaborative efforts of multiple professionals. This review provides an overview of the complexity of craniofacial disorders and dysplasias from molecular, clinical, and management perspectives.