Should soldiers take oral tranexamic acid before going into battle?

Cazes, Nicolas; Corcostegui, Simon-Pierre; Lovi, Steven; Romary, Emeric; Desrobert, Vincent; Lidzborski, Lionel; Derkenne, Clément · J Trauma Acute Care Surg · 2024

expert_opinion · Level V

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Abstract

Tranexamic acid is an inexpensive antifibrinolytic treatment that reduces morbidity and mortality in civilian and military trauma patients. It must be administered within 3 hours of the injury, and its efficacy is greater the earlier it is given. It is already used preventively in the civilian environment in a number of indications to reduce bleeding and bleeding-related mortality. We wondered about the potential benefits of preventive oral administration of tranexamic acid prior to an assault for military personnel with a potential risk of injury.

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