Hydrogen bonding enhanced drug-polymer interaction for efficient drug loading and delivery.

Qu, Xiaotian; Li, Junran; Yu, Yishu; Yang, Jie · Soft Matter · 2024

basic_science · Level V

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Abstract

A carrier design strategy of hydrogen bonding enhanced drug-carrier interaction is developed to prepare a polymeric nanomedicine with high drug loading content and superb loading efficiency. Moreover, a morphology transition from spherical to cylindrical micelles is observed upon increasing drug loading content, which can open up a new way for controlling the morphology of the polymeric nanomedicine.

Medical subject headings