Salvage Therapy Including Foscarnet and Ibalizumab for Multidrug-Resistant Human Immunodeficiency Virus Type 2 Infection.

Bachelard, Antoine; Le Hingrat, Quentin; Ferré, Valentine-Marie; Lê, Minh; Peytavin, Gilles; Damond, Florence; Charpentier, Charlotte; Fremont Goudot, Guillemette et al. · Clin Infect Dis · 2024

case_series · Level IV

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Abstract

We evaluated Ibalizumab (IBA)-containing standardized optimized salvage regimen (with or without a 4-week foscarnet induction) in individuals harboring multidrug-resistant human immunodeficiency virus type 2 (HIV-2). Nine were included; 2 achieved virological suppression after foscarnet induction with a sustained suppression at Week 24 after IBA initiation, and an additional individual at Week 24 after Ibalizumab initiation.

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