Imaging Feature of Leukoencephalopathy with Calcifications and Cysts (Labrune Syndrome).

Gaikwad, Shailesh B; Charan, Bheru Dan; Jain, Savyasachi · World Neurosurg · 2024

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Abstract

Labrune syndrome is an uncommon central nervous system disorder characterized by leukoencephalopathy, cerebral calcifications, and cysts on brain imaging. The basic pathology is microangiopathy resulting from a mutation in the SNORD118 gene. Radiological imaging is the hallmark of the disease.

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