Cartilage Injuries: Basic Science Update.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38679445.
- Also identified by DOI 10.1016/j.fcl.2023.08.002.
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Abstract
The last several decades have brought about substantial development in our understanding of the biomolecular pathways associated with chondral disease and progression to arthritis. Within domains relevant to foot and ankle, genetic modification of stem cells, augmentation of bone marrow stimulation techniques, and improvement on existing scaffolds for delivery of orthobiologic agents hold promise in improving treatment of chondral injuries. This review summarizes novel developments in the understanding of the molecular pathways underlying chondral damage and some of the recent advancements within related therapeutics.
Medical subject headings
- Cartilage, Articular