Actin pushes open a leaky lumen.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38701753.
- Also identified by DOI 10.1016/j.stem.2024.04.003.
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Abstract
Using a human stem cell-based model to understand how the human epiblast forms at the very beginning of implantation, Indana et al.<sup>1</sup> establish a role for pushing forces that are generated by apical actin polymerization and reveal a two-stage, biomechanics-driven lumen growth process underlying epiblast cavity morphogenesis.
Medical subject headings
- Actins