Safety Data Timelines for Pregnant Individuals With HIV on Antiretroviral Therapy.

Short, William R; Zimmerman, Matty M; Mohamed, Ola; Mofenson, Lynne M · Clin Infect Dis · 2024

retrospective_cohort · Level III

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Abstract

Antiretrovirals are often approved by the Food and Drug Administration without sufficient safety data regarding their use in pregnancy. To quantify this delay, we calculated the interval from the approval date to their inclusion in the Antiretroviral Pregnancy Registry prospective analysis (≥200 first-trimester exposures); the median delay was 6 years.

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