In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo.

Dunn, Andrew · Ann Intern Med · 2024

rct · Level II

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Abstract

Joosten LP, van Doorn S, van de Ven PM, et al. <b>Safety of switching from a vitamin K antagonist to a non-vitamin K antagonist oral anticoagulant in frail older patients with atrial fibrillation: results of the FRAIL-AF randomized controlled trial.</b> Circulation. 2024;149:279-289. 37634130.

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