In <i>Enterobacterales</i> bacteremia, antipseudomonal β-lactam de-escalation was noninferior to continuation for clinical cure at 3 to 5 d.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 38710092.
- Also identified by DOI 10.7326/J24-0030.
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Abstract
López-Cortés LE, Delgado-Valverde M, Moreno-Mellado E, et al; SIMPLIFY study group. <b>Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial.</b> Lancet Infect Dis. 2024;24:375-385. 38215770.
Medical subject headings
- Anti-Bacterial Agents
- Bacteremia
- beta-Lactams
- Enterobacteriaceae Infections