Associations Between Antiretroviral Regimen and Changes in Blood Pressure: Results From the D2EFT Study.

Nyein, Phyo Pyae; Petoumenos, Kathy; Borok, Margaret; Eriobu, Nnakelu; Kumarasamy, Nagalingeswaran; Avihingsanon, Anchalee; Azwa, Iskandar; Dao, Sounkalo et al. · Clin Infect Dis · 2025

rct · Level II

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Abstract

In this randomized controlled study, individuals taking dolutegravir+darunavir/ritonavir had greater increases in systolic and diastolic blood pressure than those taking 2 nucleoside reverse-transcriptase inhibitors+darunavir/ritonavir at week-48. The difference remained significant after controlling for confounding factors, including weight gain.

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