Dual stimuli-responsive upconversion nanoparticle-poly-<i>N</i>-isopropylacrylamide/DNA core-shell microgels.
basic_science · Level V
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- Record sourced from PubMed, PMID 38738402.
- Also identified by DOI 10.1039/d4sm00258j.
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Abstract
Stimuli-responsive upconversion nanoparticle (UCNP)-poly-<i>N</i>-isopropylacrylamide (pNIPAM)/DNA core-shell microgels with tunable sizes and programmable functions have been prepared. Thanks to the near-infrared (NIR)-responsive UCNP cores and thermosensitive polymeric shells, functional DNA-incorporated microgels with high DNA activity and loading efficiency are obtained, and the activity of the loaded DNA structures can be smartly regulated by NIR illumination and temperature simultaneously.