High Prevalence of Unconfirmed Positive HIV Polymerase Chain Reaction Test Results Among African Infants With HIV Exposure in the International Epidemiology Databases to Evaluate AIDS Consortium.

Carlucci, James G; Huntington, Thomas; Technau, Karl-Günter; Yotebieng, Marcel; Leroy, Valériane; Anderson, Kim; Amorissani-Folquet, Madeleine; Wools-Kaloustian, Kara et al. · Clin Infect Dis · 2024

retrospective_cohort · Level III

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Abstract

In a large, multiregional cohort of African infants with human immunodeficiency virus (HIV) exposure, 44% of those with a positive HIV polymerase chain reaction test lacked a confirmatory positive test. Efforts are needed to ensure high-fidelity implementation of HIV testing algorithms so that all positive results are confirmed.

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