Thoracic SMARCA4-Deficient Undifferentiated Tumor Mimicking a Pleural Mesothelioma on 18 F-FDG PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 38768095.
- Also identified by DOI 10.1097/RLU.0000000000005285.
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Abstract
A 72-year-old woman, who was a nonsmoker, presented with chest distress persisting for over 10 days. Plain chest CT revealed thickening of the left pleura accompanied by hydrothorax. Subsequent 18 F-FDG PET/CT showed irregular thickening involving the visceral, parietal, and interlobular pleura on the left side, with diffuse high avidity of 18 F-FDG. The left pleural mesothelioma was suspected initially, but pathological examination from biopsied specimen later confirmed a thoracic SMARCA4-deficient undifferentiated tumor.
Medical subject headings
- Fluorodeoxyglucose F18
- Positron Emission Tomography Computed Tomography
- Mesothelioma
- Pleural Neoplasms
- Transcription Factors
- DNA Helicases
- Nuclear Proteins